Oil, tar and other substances, of course, these negative factors in themselves. Follicle keratosis can not be stimulated, but with weak immunity their influence. May be fatal. In addition, diseases caused by infection. malfunctions of the nervous system and endocrine glands as well as the presence of malignant tumorsโรคลมชัก can lead to the development of this disease. Therefore, in practice, two groups of keratoses differ, acquired and genetic keratoses.